\n\n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n\n \n
\n

Product overview

\n
\n \n Made in Various\n \n INTERNATIONAL\n
\n

A weightless, multitasking pure squalane oil derived from sustainable sugarcane that rapidly hydrates from head to toe. Bioidentical to your skin's natural moisture, this single-ingredient powerhouse locks in hydration, boosts absorption of other actives, and promotes microbiome diversity for healthier-looking skin.

\n
\n Vegan Cruelty-Free EWG Verified Non-Comedogenic Fragrance-Free Dermatologist Tested Hypoallergenic Saves 2M Sharks/Year\n
\n \n \n
\n
\n
Pregnancy
\n
\n Yes
\n
\n
\n
Fungal Acne
\n
\n Yes
\n
\n
\n
Comedogenic
\n
0/5
\n
\n
\n
\n
\n
\n
Size
\n
100ml / 3.3oz
\n
\n
\n
\n
Form
\n
Pure Oil
\n
\n
\n
\n
Source
\n
Sugarcane
\n
\n
\n
\n
pH Level
\n
N/A (Oil)
\n
\n
\n
\n
Target
\n
Face/Body/Hair
\n
\n
\n \n
\n Real reviews · YouTube Shorts\n
\n
\n \n
\n
\n \n
\n
\n \n
\n
\n
\n \n
\n Why it's different\n

Bioidentical Hydration

\n

Mimics your skin's natural squalene for instant, deep moisture that feels weightless and natural.

\n
\n
\n\n\n
\n01

Texture & feel

\nSENSORY\n
\n \n
\n
\n
\n
Consistency
\n
Lightweight Oil
\n
\n
\n
\n
Scent
\n
Fragrance-Free
\n
\n
\n
\n
Absorption
\n
Instant
\n
\n
\n
\n
Finish
\n
Dewy, Non-Greasy
\n
\n
\n\n
\n
\n
\n

Bioidentical Hydration

\n

Mimics your skin's natural squalene for instant, deep moisture that feels weightless and natural.

\n
\n
\n
\n

Boosts Active Absorption

\n

Helps other skincare ingredients penetrate more deeply and work more effectively.

\n
\n
\n
\n

Sustainable Sourcing

\n

Derived from renewable sugarcane, saving 2 million sharks per year from liver harvesting.

\n
\n
\n
\n

Microbiome Support

\n

Promotes microbiome diversity for healthier, more resilient skin over time.

\n
\n
\n\n
\n02

Safety & compatibility

\nSAFE\n
\n \n
\n
\n
\n
\nPregnancy & Breastfeeding Safe\n

100% squalane contains no retinoids, salicylic acid, or any ingredients contraindicated during pregnancy. Safe for use throughout pregnancy and breastfeeding (avoid applying to areas baby's mouth contacts).

\n
\n
\n
\n
\n
\nFungal Acne (Malassezia) Safe\n

Sugarcane-derived squalane is a hydrocarbon, not a fatty acid. It cannot be metabolized by Malassezia yeast, making it one of the safest oils for fungal acne-prone skin.

\n
\n
\n
\n
\n
\nNon-Comedogenic\n

Rated 0-1 on the comedogenic scale. Pure squalane does not clog pores and is suitable for all skin types including acne-prone skin.

\n
\n
\n
\n
\n
\nSensitive Skin Approved\n

Hypoallergenic and dermatologist tested. Research shows squalane is non-irritating even at 100% concentration. Ideal for reactive and sensitive skin types.

\n
\n
\n
\n
\n
\nSafe with All Actives\n

Can be layered with retinol, vitamin C, AHAs, BHAs, and niacinamide without any interactions or irritation concerns.

\n
\n
\n
\n
\n
\nAll Ages Safe\n

Suitable for all ages from babies to elderly. Biossance states it is safe for all ages.

\n
\n
\n
\n\n
\n03

Ingredient breakdown

\nINGREDIENTS\n
\n \n
\n
\n
\n

Squalane 100%Proven\n

\n
\n

A saturated hydrocarbon that mimics squalene, a natural component of human sebum. Derived from sustainable Brazilian sugarcane through bio-fermentation, this stable, pure form provides exceptional moisturizing properties without oxidation concerns.

\n\n
\n\n
Clinical studies show 100% of subjects had increased cell renewal rate after 5 weeks of use.
\n
\n
\n\n
\n\n\n
\n

1 ingredient

\n

Squalane

\n
\nFREE FROM: Parabens, Sulfates, Phthalates, Fragrances, Essential Oils, Mineral Oil, Silicones, PEGs, Formaldehyde, Synthetic Dyes, Animal-Derived Ingredients, and 2,000+ potentially toxic or irritating ingredients banned by Biossance.\n
\n
\n
\n\n
\n04

Where it fits in your routine

\nROUTINE\n
\n \n
\n
\n
1
\n
Cleanser
\n
\n
\n
2
\n
Toner
\n
\n
\n
3
\n
Serum
\n
\n
\n
4
\n
Eye Cream
\n
\n
\n
5
\n
Moisturizer
\n
\n
\n
6
\n
Squalane Oil
\n
\n
\n \n

\n Apply as the last step to lock in all previous products. For oily skin, apply to damp skin. Can also be mixed with moisturizer or used alone.\n

\n\n
\n05

How to use

\nHOW TO USE\n
\n \n
\n
\n
1
\n
\n

For Face

\n

Warm 2-3 drops between palms. Pat gently onto face, neck, and décolleté after serums and moisturizer. For oily skin, apply to damp skin for lighter absorption.

\n
\n
\n
\n
2
\n
\n

For Body

\n

Massage a few pumps onto skin immediately after showering while skin is still damp. Focus on dry areas like elbows, knees, and heels.

\n
\n
\n
\n
3
\n
\n

For Hair

\n

Warm a small amount between hands and smooth through dry or wet hair to add shine and tame flyaways, split ends, and frizz. Can also be used as a scalp treatment.

\n
\n
\n
\n
4
\n
\n

For Lips

\n

Apply a thin layer to lips to combat dryness and prep for color. Works great as an overnight lip treatment.

\n
\n
\n
\n\n
\n06

Who is it for?

\nWHO\n
\n \n
\n
\n

\nPerfect for you if:

\n
    \n
  • \n You want a single multi-purpose oil for face, body, and hair
    • \n
  • \n You have dry, dehydrated, or aging skin
    • \n
  • \n You need a fungal acne-safe moisturizing option
    • \n
  • \n You're pregnant or breastfeeding and want safe hydration
    • \n
  • \n You have sensitive or reactive skin
    • \n
  • \n You want to boost absorption of other skincare products
    • \n
  • \n You prefer clean, sustainable beauty products
    • \n
  • \n You want a fragrance-free option
    • \n
\n
\n
\n

\nConsider alternatives if:

\n
    \n
  • \n You're looking for additional active ingredients like vitamin C or retinol
    • \n
  • \n You prefer a dropper over a pump dispenser
    • \n
  • \n You're on a strict budget (more affordable dupes exist)
    • \n
  • \n You want a scented oil experience
    • \n
  • \n You need a mattifying finish (this has a dewy finish)
    • \n
\n
\n
\n\n
\n07

Skin type compatibility

\nSKIN TYPES\n
\n \n
\n
\n
\n
Oily Skin
\nExcellent\n
\n
\n\n
\n

Lightweight and fast-absorbing. Apply to damp skin for non-greasy hydration. Helps balance oil production without clogging pores.

\n
\n
\n
\n
Dry Skin
\nExcellent\n
\n
\n\n
\n

Provides deep, lasting hydration and locks in moisture. Can be layered generously or mixed with moisturizer for extra nourishment.

\n
\n
\n
\n
Combination Skin
\nExcellent\n
\n
\n\n
\n

Balances well across different face zones. Use sparingly on T-zone and more generously on dry cheeks.

\n
\n
\n
\n
Sensitive Skin
\nExcellent\n
\n
\n\n
\n

Hypoallergenic, fragrance-free, and non-irritating. Single ingredient formula minimizes risk of reactions.

\n
\n
\n
\n
Acne-Prone Skin
\nExcellent\n
\n
\n\n
\n

Non-comedogenic (rating 0) and fungal acne safe. Won't clog pores or feed Malassezia yeast.

\n
\n
\n
\n
Mature Skin
\nExcellent\n
\n
\n\n
\n

Replenishes squalene that skin loses with age. Promotes cell renewal and improves skin elasticity.

\n
\n
\n\n
\n08

Results timeline

\nWEEK 5+\n
\n \n
\n
\nImmediately\n

Instant Hydration

\n

Skin feels instantly hydrated, soft, and smooth. Absorbs quickly without leaving a greasy residue. Provides immediate comfort to dry, tight skin.

\n95% noticed instant hydration\n
\n
\nWeek 1\n

Improved Softness

\n

Skin appears softer and smoother. Rough patches begin to improve. Overall texture feels more refined and supple.

\n95% noticed softer skin\n
\n
\nWeek 2\n

Enhanced Nourishment

\n

Skin is noticeably more nourished and hydrated. Moisture barrier is strengthened. Dullness begins to diminish.

\n93% noticed improved hydration\n
\n
\nWeek 5+\n

Cell Renewal Boost

\n

Increased cell renewal rate accelerates skin turnover by 5 days compared to untreated skin. Skin looks healthier and more radiant.

\n100% showed increased cell renewal\n
\n
\n\n
\n09

Ratings by platform

\n2K+ REVIEWS\n
\n \n
\n
\n
\n
Biossance.com
\n
\n
\n
\n
\n\n
4.8
\n
Rating
\n
\n
\n
830+
\n
Reviews
\n
\n
\n
\n Main complaint: Price point is high compared to similar squalane oils
\n
\n
\n
\n
Sephora
\n
\n
\n
\n
\n\n
4.3
\n
Rating
\n
\n
\n
500+
\n
Reviews
\n
\n
\n
\n Main complaint: Pump dispenses more product than needed
\n
\n
\n
\n
Amazon
\n
\n
\n
\n
\n\n
4.6
\n
Rating
\n
\n
\n
1,200+
\n
Reviews
\n
\n
\n
\n Main complaint: Some concerns about product authenticity from third-party sellers
\n
\n
\n
\n
Cult Beauty
\n
\n
\n
\n
\n\n
4.5
\n
Rating
\n
\n
\n
150+
\n
Reviews
\n
\n
\n
\n Main complaint: May feel slightly heavy for very oily skin types
\n
\n
\n\n
\n10

Pros & cons

\nBALANCED\n
\n \n
\n
\n

\n
Praised

\n
    \n
  • \n Ultra-lightweight and fast-absorbing
    • \n
  • \n Versatile: works on face, body, hair, and lips
    • \n
  • \n Single, pure ingredient with no additives
    • \n
  • \n Safe for all skin types including sensitive
    • \n
  • \n Fungal acne and pregnancy safe
    • \n
  • \n Sustainable, shark-friendly sourcing
    • \n
  • \n Large 100ml bottle lasts a long time
    • \n
  • \n Convenient pump dispenser
    • \n
  • \n No fragrance or irritating ingredients
    • \n
  • \n Visible results backed by clinical studies
    • \n
\n
\n
\n

\n
Criticized

\n
    \n
  • \n Higher price point than drugstore alternatives
    • \n
  • \n Pump can dispense too much product
    • \n
  • \n No additional active ingredients
    • \n
  • \n Dewy finish may not suit those wanting matte
    • \n
  • \n Plastic packaging (though recyclable)
    • \n
  • \n Some prefer dropper for precise application
    • \n
\n
\n
\n\n
\n11

Budget-friendly alternatives (dupes)

\nDUPES\n
\n \n
\n
\n100% Match
\"100%
\n
\n
The Ordinary 100% Plant-Derived Squalane
\n
\n
$7.90
\n
Budget Pick
\n
\n

Identical single-ingredient formula at a fraction of the price. Comes with dropper instead of pump. Source may vary (not specified as sugarcane). Slightly thicker texture.

\n
\n
\n
\n100% Match
\"Squalane
\n
\n
Good Molecules Squalane Oil
\n
\n
$8.00
\n
Budget Pick
\n
\n

Same 100% squalane formula. Olive-derived (slightly thicker texture). Smaller 13ml bottle but excellent value. Glass dropper packaging.

\n
\n
\n
\n100% Match
\"Squalane
\n
\n
Timeless Skin Care Squalane Oil 100% Pure
\n
\n
$14.00
\n
Similar Price
\n
\n

Olive-derived squalane with medium-weight texture. 2oz bottle with bamboo dropper. Over 5,000 reviews on Amazon. Works well as makeup primer too.

\n
\n
\n
\n100% Match
\"Squalane
\n
\n
Indeed Labs Squalane Facial Oil
\n
\n
$12.99
\n
Budget Pick
\n
\n

Sugarcane-derived like Biossance. Ultra-light \"dry oil\" texture that sinks in quickly. Clinical-grade formula. May not be hydrating enough for very dry skin.

\n
\n
\n
\n\n
\n12

Comparison with competitors

\nSIDE-BY-SIDE\n
\n \n
\n
\n
\"100%
\n
\n

Biossance 100% Squalane Oil (Featured)

\n
\n
\n
\nKey Ingredient\n100% Sugarcane Squalane\n
\n
\nSize\n100ml / 3.3oz\n
\n
\nPrice per oz\n$9.70/oz\n
\n
\nPackaging\nPump Bottle\n
\n
\nTexture\nUltra-Lightweight\n
\n
\nFungal Acne Safe\nYes\n
\n
\n
\n
\n
\"100%
\n
\n

The Ordinary 100% Squalane

\n
\n
\n
\nKey Ingredient\n100% Plant-Derived Squalane\n
\n
\nSize\n30ml / 1oz\n
\n
\nPrice per oz\n$7.90/oz\n
\n
\nPackaging\nDropper Bottle\n
\n
\nTexture\nMedium-Weight\n
\n
\nFungal Acne Safe\nYes\n
\n
\n
\n
\n
\"Squalane
\n
\n

Good Molecules Squalane Oil

\n
\n
\n
\nKey Ingredient\n100% Olive-Derived Squalane\n
\n
\nSize\n13ml / 0.44oz\n
\n
\nPrice per oz\n$18.18/oz\n
\n
\nPackaging\nGlass Dropper\n
\n
\nTexture\nSlightly Thicker\n
\n
\nFungal Acne Safe\nYes\n
\n
\n
\n
\n
\"Squalane
\n
\n

Timeless Squalane Oil 100% Pure

\n
\n
\n
\nKey Ingredient\n100% Olive-Derived Squalane\n
\n
\nSize\n60ml / 2oz\n
\n
\nPrice per oz\n$7.00/oz\n
\n
\nPackaging\nBamboo Dropper\n
\n
\nTexture\nMedium-Weight\n
\n
\nFungal Acne Safe\nYes\n
\n
\n
\n
\n\n
\n13

Storage & shelf life

\n12 MONTHS\n
\n \n
\n
\n
\n
\nPeriod After Opening (PAO)\n

12 months after opening. Squalane is highly stable and resistant to oxidation.

\n
\n
\n
\n
\n
\nStorage\n

Store in a cool, dry place away from direct sunlight. No refrigeration required. Keep bottle closed when not in use.

\n
\n
\n
\n
\n
\nPackaging\n

Recyclable pump bottle. Once empty, dispose of pump and rinse bottle for curbside recycling. Outer carton is FSC-certified sugarcane paper.

\n
\n
\n
\n
\n
\nTravel Friendly\n

100ml size exceeds TSA carry-on limits. Travel size (30ml) available separately for air travel. Pump bottle is spill-resistant.

\n
\n
\n
\n\n
\n13

Frequently asked questions

\nFAQ\n
\n \n
\n
\n\n\n
\n

Yes, absolutely. This product contains only 100% pure squalane with no retinoids, salicylic acid, hydroquinone, chemical sunscreens, or any other ingredients that are contraindicated during pregnancy. Squalane is considered completely safe for use throughout pregnancy and breastfeeding. The only precaution: avoid applying to areas that may come in contact with baby's mouth while nursing.

\n
\n
\n
\n\n\n
\n

Yes, this is one of the safest oils for fungal acne-prone skin. Sugarcane-derived squalane is a hydrocarbon (made only of carbon and hydrogen), not a fatty acid or triglyceride. Malassezia yeast cannot metabolize squalane, making it completely safe. In fact, dermatologists often recommend squalane as one of the few oils that won't trigger fungal acne flares.

\n
\n
\n
\n\n\n
\n

Yes, squalane is compatible with all actives including retinol, vitamin C, AHAs, BHAs, niacinamide, and peptides. It has no pH concerns or interaction issues. In fact, applying squalane after these actives can help seal them in, reduce irritation, and enhance their absorption. It's an excellent \"finishing\" product for any routine.

\n
\n
\n
\n\n\n
\n

This squalane oil works excellently for all skin types: dry (deep hydration), oily (apply to damp skin for lightweight moisture), combination (adjust amount by zone), sensitive (hypoallergenic single ingredient), acne-prone (non-comedogenic), and mature (replaces naturally declining squalene). Its versatility is one of its greatest strengths.

\n
\n
\n
\n\n\n
\n

Instant results: 95% of users feel immediately hydrated skin. Week 1: Skin feels softer and smoother. Week 2: 93% notice improved nourishment and hydration. Week 5+: Clinical studies show 100% of users experienced increased cell renewal rate, with skin turnover accelerating by 5 days.

\n
\n
\n
\n\n\n
\n

Apply as your last step (after moisturizer) to seal in all previous products. The order is: Cleanser → Toner → Serum → Eye Cream → Moisturizer → Squalane Oil. You can also mix a few drops into your moisturizer, use it alone on damp skin, or apply it any time your skin needs extra hydration.

\n
\n
\n
\n\n\n
\n

No, squalane has a comedogenic rating of 0-1, meaning it is non-comedogenic and will not clog pores. It's one of the few oils recommended for acne-prone skin. Biossance's formula is dermatologist tested, hypoallergenic, and specifically designed to be safe for all skin types including acne-prone.

\n
\n
\n
\n\n\n
\n

The product has a PAO (Period After Opening) of 12 months. Squalane is the hydrogenated, stable form of squalene, which means it's highly resistant to oxidation and has a long shelf life. Store in a cool, dry place away from direct sunlight for best results.

\n
\n
\n
\n\n
\n
— Skincarisma verdict
\n
\n 4.6\n / 5\n ★★★★★\n
\n

\nVerdict: Biossance 100% Squalane Oil is a premium, sustainably-sourced hydration powerhouse that delivers on its promises. Its single-ingredient purity makes it ideal for sensitive skin, fungal acne sufferers, and pregnant/breastfeeding individuals. While budget alternatives like The Ordinary offer similar formulas at lower prices, Biossance's ultra-lightweight sugarcane-derived texture, convenient pump packaging, and commitment to saving 2 million sharks annually justify the premium for those who value clean beauty and sustainability. A versatile must-have for any skincare routine.\n

\n
\n\n
\n

Browse related

\n
\n
\n By Concern\n Dryness\n Sensitive Skin\n
\n
\n By Brand & Origin\n US Brands\n More from Biossance\n
\n
\n Filters\n Cruelty-Free\n Fragrance-Free\n Fungal Acne Safe\n
\n
\n
\n \n \n\n","image":["/images/skca.shop/images/product/100-squalane-oil-1.jpg"],"sku":"100-squalane-oil","brand":{"@type":"Brand","name":"Skincarisma"},"offers":{"@type":"AggregateOffer","lowPrice":34,"highPrice":34,"priceCurrency":"USD","availability":"https://schema.org/InStock","url":"https://skca.shop/products/100-squalane-oil","offerCount":1}}
HomeStore

100% Squalane Oil

Product image 1

100% Squalane Oil

Product overview

Made in Various INTERNATIONAL

A weightless, multitasking pure squalane oil derived from sustainable sugarcane that rapidly hydrates from head to toe. Bioidentical to your skin's natural moisture, this single-ingredient powerhouse locks in hydration, boosts absorption of other actives, and promotes microbiome diversity for healthier-looking skin.

Vegan Cruelty-Free EWG Verified Non-Comedogenic Fragrance-Free Dermatologist Tested Hypoallergenic Saves 2M Sharks/Year
Pregnancy
Yes
Fungal Acne
Yes
Comedogenic
0/5
Size
100ml / 3.3oz
Form
Pure Oil
Source
Sugarcane
pH Level
N/A (Oil)
Target
Face/Body/Hair
Real reviews · YouTube Shorts
Why it's different

Bioidentical Hydration

Mimics your skin's natural squalene for instant, deep moisture that feels weightless and natural.

01

Texture & feel

SENSORY
Consistency
Lightweight Oil
Scent
Fragrance-Free
Absorption
Instant
Finish
Dewy, Non-Greasy

Bioidentical Hydration

Mimics your skin's natural squalene for instant, deep moisture that feels weightless and natural.

Boosts Active Absorption

Helps other skincare ingredients penetrate more deeply and work more effectively.

Sustainable Sourcing

Derived from renewable sugarcane, saving 2 million sharks per year from liver harvesting.

Microbiome Support

Promotes microbiome diversity for healthier, more resilient skin over time.

02

Safety & compatibility

SAFE
Pregnancy & Breastfeeding Safe

100% squalane contains no retinoids, salicylic acid, or any ingredients contraindicated during pregnancy. Safe for use throughout pregnancy and breastfeeding (avoid applying to areas baby's mouth contacts).

Fungal Acne (Malassezia) Safe

Sugarcane-derived squalane is a hydrocarbon, not a fatty acid. It cannot be metabolized by Malassezia yeast, making it one of the safest oils for fungal acne-prone skin.

Non-Comedogenic

Rated 0-1 on the comedogenic scale. Pure squalane does not clog pores and is suitable for all skin types including acne-prone skin.

Sensitive Skin Approved

Hypoallergenic and dermatologist tested. Research shows squalane is non-irritating even at 100% concentration. Ideal for reactive and sensitive skin types.

Safe with All Actives

Can be layered with retinol, vitamin C, AHAs, BHAs, and niacinamide without any interactions or irritation concerns.

All Ages Safe

Suitable for all ages from babies to elderly. Biossance states it is safe for all ages.

03

Ingredient breakdown

INGREDIENTS

Squalane 100%Proven

A saturated hydrocarbon that mimics squalene, a natural component of human sebum. Derived from sustainable Brazilian sugarcane through bio-fermentation, this stable, pure form provides exceptional moisturizing properties without oxidation concerns.

  • Mechanism: Creates a protective barrier that prevents transepidermal water loss (TEWL) while allowing skin to breathe
  • Research: Studies show squalane is non-irritating even at 100% concentration (Cosmetic Ingredient Review)
  • Bioidentical: Mirrors the squalene naturally produced by your skin, which decreases with age after mid-20s
  • Stability: Hydrogenated form has a long shelf life and won't oxidize like squalene
Clinical studies show 100% of subjects had increased cell renewal rate after 5 weeks of use.

1 ingredient

Squalane

FREE FROM: Parabens, Sulfates, Phthalates, Fragrances, Essential Oils, Mineral Oil, Silicones, PEGs, Formaldehyde, Synthetic Dyes, Animal-Derived Ingredients, and 2,000+ potentially toxic or irritating ingredients banned by Biossance.
04

Where it fits in your routine

ROUTINE
1
Cleanser
2
Toner
3
Serum
4
Eye Cream
5
Moisturizer
6
Squalane Oil

Apply as the last step to lock in all previous products. For oily skin, apply to damp skin. Can also be mixed with moisturizer or used alone.

05

How to use

HOW TO USE
1

For Face

Warm 2-3 drops between palms. Pat gently onto face, neck, and décolleté after serums and moisturizer. For oily skin, apply to damp skin for lighter absorption.

2

For Body

Massage a few pumps onto skin immediately after showering while skin is still damp. Focus on dry areas like elbows, knees, and heels.

3

For Hair

Warm a small amount between hands and smooth through dry or wet hair to add shine and tame flyaways, split ends, and frizz. Can also be used as a scalp treatment.

4

For Lips

Apply a thin layer to lips to combat dryness and prep for color. Works great as an overnight lip treatment.

06

Who is it for?

WHO

Perfect for you if:

  • You want a single multi-purpose oil for face, body, and hair
  • You have dry, dehydrated, or aging skin
  • You need a fungal acne-safe moisturizing option
  • You're pregnant or breastfeeding and want safe hydration
  • You have sensitive or reactive skin
  • You want to boost absorption of other skincare products
  • You prefer clean, sustainable beauty products
  • You want a fragrance-free option

Consider alternatives if:

  • You're looking for additional active ingredients like vitamin C or retinol
  • You prefer a dropper over a pump dispenser
  • You're on a strict budget (more affordable dupes exist)
  • You want a scented oil experience
  • You need a mattifying finish (this has a dewy finish)
07

Skin type compatibility

SKIN TYPES
Oily Skin
Excellent

Lightweight and fast-absorbing. Apply to damp skin for non-greasy hydration. Helps balance oil production without clogging pores.

Dry Skin
Excellent

Provides deep, lasting hydration and locks in moisture. Can be layered generously or mixed with moisturizer for extra nourishment.

Combination Skin
Excellent

Balances well across different face zones. Use sparingly on T-zone and more generously on dry cheeks.

Sensitive Skin
Excellent

Hypoallergenic, fragrance-free, and non-irritating. Single ingredient formula minimizes risk of reactions.

Acne-Prone Skin
Excellent

Non-comedogenic (rating 0) and fungal acne safe. Won't clog pores or feed Malassezia yeast.

Mature Skin
Excellent

Replenishes squalene that skin loses with age. Promotes cell renewal and improves skin elasticity.

08

Results timeline

WEEK 5+
Immediately

Instant Hydration

Skin feels instantly hydrated, soft, and smooth. Absorbs quickly without leaving a greasy residue. Provides immediate comfort to dry, tight skin.

95% noticed instant hydration
Week 1

Improved Softness

Skin appears softer and smoother. Rough patches begin to improve. Overall texture feels more refined and supple.

95% noticed softer skin
Week 2

Enhanced Nourishment

Skin is noticeably more nourished and hydrated. Moisture barrier is strengthened. Dullness begins to diminish.

93% noticed improved hydration
Week 5+

Cell Renewal Boost

Increased cell renewal rate accelerates skin turnover by 5 days compared to untreated skin. Skin looks healthier and more radiant.

100% showed increased cell renewal
09

Ratings by platform

2K+ REVIEWS
Biossance.com
4.8
Rating
830+
Reviews
Main complaint: Price point is high compared to similar squalane oils
Sephora
4.3
Rating
500+
Reviews
Main complaint: Pump dispenses more product than needed
Amazon
4.6
Rating
1,200+
Reviews
Main complaint: Some concerns about product authenticity from third-party sellers
Cult Beauty
4.5
Rating
150+
Reviews
Main complaint: May feel slightly heavy for very oily skin types
10

Pros & cons

BALANCED

Praised

  • Ultra-lightweight and fast-absorbing
  • Versatile: works on face, body, hair, and lips
  • Single, pure ingredient with no additives
  • Safe for all skin types including sensitive
  • Fungal acne and pregnancy safe
  • Sustainable, shark-friendly sourcing
  • Large 100ml bottle lasts a long time
  • Convenient pump dispenser
  • No fragrance or irritating ingredients
  • Visible results backed by clinical studies

Criticized

  • Higher price point than drugstore alternatives
  • Pump can dispense too much product
  • No additional active ingredients
  • Dewy finish may not suit those wanting matte
  • Plastic packaging (though recyclable)
  • Some prefer dropper for precise application
11

Budget-friendly alternatives (dupes)

DUPES
100% Match
100% Plant-Derived Squalane
The Ordinary 100% Plant-Derived Squalane
$7.90
Budget Pick

Identical single-ingredient formula at a fraction of the price. Comes with dropper instead of pump. Source may vary (not specified as sugarcane). Slightly thicker texture.

100% Match
Squalane Oil
Good Molecules Squalane Oil
$8.00
Budget Pick

Same 100% squalane formula. Olive-derived (slightly thicker texture). Smaller 13ml bottle but excellent value. Glass dropper packaging.

100% Match
Squalane Oil 100% Pure
Timeless Skin Care Squalane Oil 100% Pure
$14.00
Similar Price

Olive-derived squalane with medium-weight texture. 2oz bottle with bamboo dropper. Over 5,000 reviews on Amazon. Works well as makeup primer too.

100% Match
Squalane Facial Oil
Indeed Labs Squalane Facial Oil
$12.99
Budget Pick

Sugarcane-derived like Biossance. Ultra-light "dry oil" texture that sinks in quickly. Clinical-grade formula. May not be hydrating enough for very dry skin.

12

Comparison with competitors

SIDE-BY-SIDE
100% Squalane Oil

Biossance 100% Squalane Oil (Featured)

Key Ingredient 100% Sugarcane Squalane
Size 100ml / 3.3oz
Price per oz $9.70/oz
Packaging Pump Bottle
Texture Ultra-Lightweight
Fungal Acne Safe Yes
100% Plant-Derived Squalane

The Ordinary 100% Squalane

Key Ingredient 100% Plant-Derived Squalane
Size 30ml / 1oz
Price per oz $7.90/oz
Packaging Dropper Bottle
Texture Medium-Weight
Fungal Acne Safe Yes
Squalane Oil

Good Molecules Squalane Oil

Key Ingredient 100% Olive-Derived Squalane
Size 13ml / 0.44oz
Price per oz $18.18/oz
Packaging Glass Dropper
Texture Slightly Thicker
Fungal Acne Safe Yes
Squalane Oil 100% Pure

Timeless Squalane Oil 100% Pure

Key Ingredient 100% Olive-Derived Squalane
Size 60ml / 2oz
Price per oz $7.00/oz
Packaging Bamboo Dropper
Texture Medium-Weight
Fungal Acne Safe Yes
13

Storage & shelf life

12 MONTHS
Period After Opening (PAO)

12 months after opening. Squalane is highly stable and resistant to oxidation.

Storage

Store in a cool, dry place away from direct sunlight. No refrigeration required. Keep bottle closed when not in use.

Packaging

Recyclable pump bottle. Once empty, dispose of pump and rinse bottle for curbside recycling. Outer carton is FSC-certified sugarcane paper.

Travel Friendly

100ml size exceeds TSA carry-on limits. Travel size (30ml) available separately for air travel. Pump bottle is spill-resistant.

13

Frequently asked questions

FAQ

Yes, absolutely. This product contains only 100% pure squalane with no retinoids, salicylic acid, hydroquinone, chemical sunscreens, or any other ingredients that are contraindicated during pregnancy. Squalane is considered completely safe for use throughout pregnancy and breastfeeding. The only precaution: avoid applying to areas that may come in contact with baby's mouth while nursing.

Yes, this is one of the safest oils for fungal acne-prone skin. Sugarcane-derived squalane is a hydrocarbon (made only of carbon and hydrogen), not a fatty acid or triglyceride. Malassezia yeast cannot metabolize squalane, making it completely safe. In fact, dermatologists often recommend squalane as one of the few oils that won't trigger fungal acne flares.

Yes, squalane is compatible with all actives including retinol, vitamin C, AHAs, BHAs, niacinamide, and peptides. It has no pH concerns or interaction issues. In fact, applying squalane after these actives can help seal them in, reduce irritation, and enhance their absorption. It's an excellent "finishing" product for any routine.

This squalane oil works excellently for all skin types: dry (deep hydration), oily (apply to damp skin for lightweight moisture), combination (adjust amount by zone), sensitive (hypoallergenic single ingredient), acne-prone (non-comedogenic), and mature (replaces naturally declining squalene). Its versatility is one of its greatest strengths.

Instant results: 95% of users feel immediately hydrated skin. Week 1: Skin feels softer and smoother. Week 2: 93% notice improved nourishment and hydration. Week 5+: Clinical studies show 100% of users experienced increased cell renewal rate, with skin turnover accelerating by 5 days.

Apply as your last step (after moisturizer) to seal in all previous products. The order is: Cleanser → Toner → Serum → Eye Cream → Moisturizer → Squalane Oil. You can also mix a few drops into your moisturizer, use it alone on damp skin, or apply it any time your skin needs extra hydration.

No, squalane has a comedogenic rating of 0-1, meaning it is non-comedogenic and will not clog pores. It's one of the few oils recommended for acne-prone skin. Biossance's formula is dermatologist tested, hypoallergenic, and specifically designed to be safe for all skin types including acne-prone.

The product has a PAO (Period After Opening) of 12 months. Squalane is the hydrogenated, stable form of squalene, which means it's highly resistant to oxidation and has a long shelf life. Store in a cool, dry place away from direct sunlight for best results.

— Skincarisma verdict
4.6 / 5 ★★★★★

Verdict: Biossance 100% Squalane Oil is a premium, sustainably-sourced hydration powerhouse that delivers on its promises. Its single-ingredient purity makes it ideal for sensitive skin, fungal acne sufferers, and pregnant/breastfeeding individuals. While budget alternatives like The Ordinary offer similar formulas at lower prices, Biossance's ultra-lightweight sugarcane-derived texture, convenient pump packaging, and commitment to saving 2 million sharks annually justify the premium for those who value clean beauty and sustainability. A versatile must-have for any skincare routine.

Browse related

By Concern Dryness Sensitive Skin
By Brand & Origin US Brands More from Biossance
Filters Cruelty-Free Fragrance-Free Fungal Acne Safe
$34.00
100% Squalane Oil—
$34.00

Product Information

Shipping & Returns

Description

Product overview

Made in Various INTERNATIONAL

A weightless, multitasking pure squalane oil derived from sustainable sugarcane that rapidly hydrates from head to toe. Bioidentical to your skin's natural moisture, this single-ingredient powerhouse locks in hydration, boosts absorption of other actives, and promotes microbiome diversity for healthier-looking skin.

Vegan Cruelty-Free EWG Verified Non-Comedogenic Fragrance-Free Dermatologist Tested Hypoallergenic Saves 2M Sharks/Year
Pregnancy
Yes
Fungal Acne
Yes
Comedogenic
0/5
Size
100ml / 3.3oz
Form
Pure Oil
Source
Sugarcane
pH Level
N/A (Oil)
Target
Face/Body/Hair
Real reviews · YouTube Shorts
Why it's different

Bioidentical Hydration

Mimics your skin's natural squalene for instant, deep moisture that feels weightless and natural.

01

Texture & feel

SENSORY
Consistency
Lightweight Oil
Scent
Fragrance-Free
Absorption
Instant
Finish
Dewy, Non-Greasy

Bioidentical Hydration

Mimics your skin's natural squalene for instant, deep moisture that feels weightless and natural.

Boosts Active Absorption

Helps other skincare ingredients penetrate more deeply and work more effectively.

Sustainable Sourcing

Derived from renewable sugarcane, saving 2 million sharks per year from liver harvesting.

Microbiome Support

Promotes microbiome diversity for healthier, more resilient skin over time.

02

Safety & compatibility

SAFE
Pregnancy & Breastfeeding Safe

100% squalane contains no retinoids, salicylic acid, or any ingredients contraindicated during pregnancy. Safe for use throughout pregnancy and breastfeeding (avoid applying to areas baby's mouth contacts).

Fungal Acne (Malassezia) Safe

Sugarcane-derived squalane is a hydrocarbon, not a fatty acid. It cannot be metabolized by Malassezia yeast, making it one of the safest oils for fungal acne-prone skin.

Non-Comedogenic

Rated 0-1 on the comedogenic scale. Pure squalane does not clog pores and is suitable for all skin types including acne-prone skin.

Sensitive Skin Approved

Hypoallergenic and dermatologist tested. Research shows squalane is non-irritating even at 100% concentration. Ideal for reactive and sensitive skin types.

Safe with All Actives

Can be layered with retinol, vitamin C, AHAs, BHAs, and niacinamide without any interactions or irritation concerns.

All Ages Safe

Suitable for all ages from babies to elderly. Biossance states it is safe for all ages.

03

Ingredient breakdown

INGREDIENTS

Squalane 100%Proven

A saturated hydrocarbon that mimics squalene, a natural component of human sebum. Derived from sustainable Brazilian sugarcane through bio-fermentation, this stable, pure form provides exceptional moisturizing properties without oxidation concerns.

  • Mechanism: Creates a protective barrier that prevents transepidermal water loss (TEWL) while allowing skin to breathe
  • Research: Studies show squalane is non-irritating even at 100% concentration (Cosmetic Ingredient Review)
  • Bioidentical: Mirrors the squalene naturally produced by your skin, which decreases with age after mid-20s
  • Stability: Hydrogenated form has a long shelf life and won't oxidize like squalene
Clinical studies show 100% of subjects had increased cell renewal rate after 5 weeks of use.

1 ingredient

Squalane

FREE FROM: Parabens, Sulfates, Phthalates, Fragrances, Essential Oils, Mineral Oil, Silicones, PEGs, Formaldehyde, Synthetic Dyes, Animal-Derived Ingredients, and 2,000+ potentially toxic or irritating ingredients banned by Biossance.
04

Where it fits in your routine

ROUTINE
1
Cleanser
2
Toner
3
Serum
4
Eye Cream
5
Moisturizer
6
Squalane Oil

Apply as the last step to lock in all previous products. For oily skin, apply to damp skin. Can also be mixed with moisturizer or used alone.

05

How to use

HOW TO USE
1

For Face

Warm 2-3 drops between palms. Pat gently onto face, neck, and décolleté after serums and moisturizer. For oily skin, apply to damp skin for lighter absorption.

2

For Body

Massage a few pumps onto skin immediately after showering while skin is still damp. Focus on dry areas like elbows, knees, and heels.

3

For Hair

Warm a small amount between hands and smooth through dry or wet hair to add shine and tame flyaways, split ends, and frizz. Can also be used as a scalp treatment.

4

For Lips

Apply a thin layer to lips to combat dryness and prep for color. Works great as an overnight lip treatment.

06

Who is it for?

WHO

Perfect for you if:

  • You want a single multi-purpose oil for face, body, and hair
  • You have dry, dehydrated, or aging skin
  • You need a fungal acne-safe moisturizing option
  • You're pregnant or breastfeeding and want safe hydration
  • You have sensitive or reactive skin
  • You want to boost absorption of other skincare products
  • You prefer clean, sustainable beauty products
  • You want a fragrance-free option

Consider alternatives if:

  • You're looking for additional active ingredients like vitamin C or retinol
  • You prefer a dropper over a pump dispenser
  • You're on a strict budget (more affordable dupes exist)
  • You want a scented oil experience
  • You need a mattifying finish (this has a dewy finish)
07

Skin type compatibility

SKIN TYPES
Oily Skin
Excellent

Lightweight and fast-absorbing. Apply to damp skin for non-greasy hydration. Helps balance oil production without clogging pores.

Dry Skin
Excellent

Provides deep, lasting hydration and locks in moisture. Can be layered generously or mixed with moisturizer for extra nourishment.

Combination Skin
Excellent

Balances well across different face zones. Use sparingly on T-zone and more generously on dry cheeks.

Sensitive Skin
Excellent

Hypoallergenic, fragrance-free, and non-irritating. Single ingredient formula minimizes risk of reactions.

Acne-Prone Skin
Excellent

Non-comedogenic (rating 0) and fungal acne safe. Won't clog pores or feed Malassezia yeast.

Mature Skin
Excellent

Replenishes squalene that skin loses with age. Promotes cell renewal and improves skin elasticity.

08

Results timeline

WEEK 5+
Immediately

Instant Hydration

Skin feels instantly hydrated, soft, and smooth. Absorbs quickly without leaving a greasy residue. Provides immediate comfort to dry, tight skin.

95% noticed instant hydration
Week 1

Improved Softness

Skin appears softer and smoother. Rough patches begin to improve. Overall texture feels more refined and supple.

95% noticed softer skin
Week 2

Enhanced Nourishment

Skin is noticeably more nourished and hydrated. Moisture barrier is strengthened. Dullness begins to diminish.

93% noticed improved hydration
Week 5+

Cell Renewal Boost

Increased cell renewal rate accelerates skin turnover by 5 days compared to untreated skin. Skin looks healthier and more radiant.

100% showed increased cell renewal
09

Ratings by platform

2K+ REVIEWS
Biossance.com
4.8
Rating
830+
Reviews
Main complaint: Price point is high compared to similar squalane oils
Sephora
4.3
Rating
500+
Reviews
Main complaint: Pump dispenses more product than needed
Amazon
4.6
Rating
1,200+
Reviews
Main complaint: Some concerns about product authenticity from third-party sellers
Cult Beauty
4.5
Rating
150+
Reviews
Main complaint: May feel slightly heavy for very oily skin types
10

Pros & cons

BALANCED

Praised

  • Ultra-lightweight and fast-absorbing
  • Versatile: works on face, body, hair, and lips
  • Single, pure ingredient with no additives
  • Safe for all skin types including sensitive
  • Fungal acne and pregnancy safe
  • Sustainable, shark-friendly sourcing
  • Large 100ml bottle lasts a long time
  • Convenient pump dispenser
  • No fragrance or irritating ingredients
  • Visible results backed by clinical studies

Criticized

  • Higher price point than drugstore alternatives
  • Pump can dispense too much product
  • No additional active ingredients
  • Dewy finish may not suit those wanting matte
  • Plastic packaging (though recyclable)
  • Some prefer dropper for precise application
11

Budget-friendly alternatives (dupes)

DUPES
100% Match
100% Plant-Derived Squalane
The Ordinary 100% Plant-Derived Squalane
$7.90
Budget Pick

Identical single-ingredient formula at a fraction of the price. Comes with dropper instead of pump. Source may vary (not specified as sugarcane). Slightly thicker texture.

100% Match
Squalane Oil
Good Molecules Squalane Oil
$8.00
Budget Pick

Same 100% squalane formula. Olive-derived (slightly thicker texture). Smaller 13ml bottle but excellent value. Glass dropper packaging.

100% Match
Squalane Oil 100% Pure
Timeless Skin Care Squalane Oil 100% Pure
$14.00
Similar Price

Olive-derived squalane with medium-weight texture. 2oz bottle with bamboo dropper. Over 5,000 reviews on Amazon. Works well as makeup primer too.

100% Match
Squalane Facial Oil
Indeed Labs Squalane Facial Oil
$12.99
Budget Pick

Sugarcane-derived like Biossance. Ultra-light "dry oil" texture that sinks in quickly. Clinical-grade formula. May not be hydrating enough for very dry skin.

12

Comparison with competitors

SIDE-BY-SIDE
100% Squalane Oil

Biossance 100% Squalane Oil (Featured)

Key Ingredient 100% Sugarcane Squalane
Size 100ml / 3.3oz
Price per oz $9.70/oz
Packaging Pump Bottle
Texture Ultra-Lightweight
Fungal Acne Safe Yes
100% Plant-Derived Squalane

The Ordinary 100% Squalane

Key Ingredient 100% Plant-Derived Squalane
Size 30ml / 1oz
Price per oz $7.90/oz
Packaging Dropper Bottle
Texture Medium-Weight
Fungal Acne Safe Yes
Squalane Oil

Good Molecules Squalane Oil

Key Ingredient 100% Olive-Derived Squalane
Size 13ml / 0.44oz
Price per oz $18.18/oz
Packaging Glass Dropper
Texture Slightly Thicker
Fungal Acne Safe Yes
Squalane Oil 100% Pure

Timeless Squalane Oil 100% Pure

Key Ingredient 100% Olive-Derived Squalane
Size 60ml / 2oz
Price per oz $7.00/oz
Packaging Bamboo Dropper
Texture Medium-Weight
Fungal Acne Safe Yes
13

Storage & shelf life

12 MONTHS
Period After Opening (PAO)

12 months after opening. Squalane is highly stable and resistant to oxidation.

Storage

Store in a cool, dry place away from direct sunlight. No refrigeration required. Keep bottle closed when not in use.

Packaging

Recyclable pump bottle. Once empty, dispose of pump and rinse bottle for curbside recycling. Outer carton is FSC-certified sugarcane paper.

Travel Friendly

100ml size exceeds TSA carry-on limits. Travel size (30ml) available separately for air travel. Pump bottle is spill-resistant.

13

Frequently asked questions

FAQ

Yes, absolutely. This product contains only 100% pure squalane with no retinoids, salicylic acid, hydroquinone, chemical sunscreens, or any other ingredients that are contraindicated during pregnancy. Squalane is considered completely safe for use throughout pregnancy and breastfeeding. The only precaution: avoid applying to areas that may come in contact with baby's mouth while nursing.

Yes, this is one of the safest oils for fungal acne-prone skin. Sugarcane-derived squalane is a hydrocarbon (made only of carbon and hydrogen), not a fatty acid or triglyceride. Malassezia yeast cannot metabolize squalane, making it completely safe. In fact, dermatologists often recommend squalane as one of the few oils that won't trigger fungal acne flares.

Yes, squalane is compatible with all actives including retinol, vitamin C, AHAs, BHAs, niacinamide, and peptides. It has no pH concerns or interaction issues. In fact, applying squalane after these actives can help seal them in, reduce irritation, and enhance their absorption. It's an excellent "finishing" product for any routine.

This squalane oil works excellently for all skin types: dry (deep hydration), oily (apply to damp skin for lightweight moisture), combination (adjust amount by zone), sensitive (hypoallergenic single ingredient), acne-prone (non-comedogenic), and mature (replaces naturally declining squalene). Its versatility is one of its greatest strengths.

Instant results: 95% of users feel immediately hydrated skin. Week 1: Skin feels softer and smoother. Week 2: 93% notice improved nourishment and hydration. Week 5+: Clinical studies show 100% of users experienced increased cell renewal rate, with skin turnover accelerating by 5 days.

Apply as your last step (after moisturizer) to seal in all previous products. The order is: Cleanser → Toner → Serum → Eye Cream → Moisturizer → Squalane Oil. You can also mix a few drops into your moisturizer, use it alone on damp skin, or apply it any time your skin needs extra hydration.

No, squalane has a comedogenic rating of 0-1, meaning it is non-comedogenic and will not clog pores. It's one of the few oils recommended for acne-prone skin. Biossance's formula is dermatologist tested, hypoallergenic, and specifically designed to be safe for all skin types including acne-prone.

The product has a PAO (Period After Opening) of 12 months. Squalane is the hydrogenated, stable form of squalene, which means it's highly resistant to oxidation and has a long shelf life. Store in a cool, dry place away from direct sunlight for best results.

— Skincarisma verdict
4.6 / 5 ★★★★★

Verdict: Biossance 100% Squalane Oil is a premium, sustainably-sourced hydration powerhouse that delivers on its promises. Its single-ingredient purity makes it ideal for sensitive skin, fungal acne sufferers, and pregnant/breastfeeding individuals. While budget alternatives like The Ordinary offer similar formulas at lower prices, Biossance's ultra-lightweight sugarcane-derived texture, convenient pump packaging, and commitment to saving 2 million sharks annually justify the premium for those who value clean beauty and sustainability. A versatile must-have for any skincare routine.

Browse related

By Concern Dryness Sensitive Skin
By Brand & Origin US Brands More from Biossance
Filters Cruelty-Free Fragrance-Free Fungal Acne Safe