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A weightless, multitasking pure squalane oil derived from sustainable sugarcane that rapidly hydrates from head to toe. Bioidentical to your skin's natural moisture, this single-ingredient powerhouse locks in hydration, boosts absorption of other actives, and promotes microbiome diversity for healthier-looking skin.

Vegan Cruelty-Free EWG Verified Non-Comedogenic Fragrance-Free Dermatologist Tested Hypoallergenic Saves 2M Sharks/Year

Pregnancy

Yes

Fungal Acne

Yes

Comedogenic

0/5

Size

100ml / 3.3oz

Form

Pure Oil

Source

Sugarcane

pH Level

N/A (Oil)

Target

Face/Body/Hair

Real reviews · YouTube Shorts

Why it's different

Bioidentical Hydration

Mimics your skin's natural squalene for instant, deep moisture that feels weightless and natural.

Texture & feel

SENSORY

Consistency

Lightweight Oil

Scent

Fragrance-Free

Absorption

Instant

Finish

Dewy, Non-Greasy

Bioidentical Hydration

Mimics your skin's natural squalene for instant, deep moisture that feels weightless and natural.

Boosts Active Absorption

Helps other skincare ingredients penetrate more deeply and work more effectively.

Sustainable Sourcing

Derived from renewable sugarcane, saving 2 million sharks per year from liver harvesting.

Microbiome Support

Promotes microbiome diversity for healthier, more resilient skin over time.

Safety & compatibility

SAFE

Pregnancy & Breastfeeding Safe

100% squalane contains no retinoids, salicylic acid, or any ingredients contraindicated during pregnancy. Safe for use throughout pregnancy and breastfeeding (avoid applying to areas baby's mouth contacts).

Fungal Acne (Malassezia) Safe

Sugarcane-derived squalane is a hydrocarbon, not a fatty acid. It cannot be metabolized by Malassezia yeast, making it one of the safest oils for fungal acne-prone skin.

Non-Comedogenic

Rated 0-1 on the comedogenic scale. Pure squalane does not clog pores and is suitable for all skin types including acne-prone skin.

Sensitive Skin Approved

Hypoallergenic and dermatologist tested. Research shows squalane is non-irritating even at 100% concentration. Ideal for reactive and sensitive skin types.

Safe with All Actives

Can be layered with retinol, vitamin C, AHAs, BHAs, and niacinamide without any interactions or irritation concerns.

All Ages Safe

Suitable for all ages from babies to elderly. Biossance states it is safe for all ages.

Ingredient breakdown

INGREDIENTS

Squalane 100%Proven

A saturated hydrocarbon that mimics squalene, a natural component of human sebum. Derived from sustainable Brazilian sugarcane through bio-fermentation, this stable, pure form provides exceptional moisturizing properties without oxidation concerns.

Mechanism: Creates a protective barrier that prevents transepidermal water loss (TEWL) while allowing skin to breathe
Research: Studies show squalane is non-irritating even at 100% concentration (Cosmetic Ingredient Review)
Bioidentical: Mirrors the squalene naturally produced by your skin, which decreases with age after mid-20s
Stability: Hydrogenated form has a long shelf life and won't oxidize like squalene

Clinical studies show 100% of subjects had increased cell renewal rate after 5 weeks of use.

Full Ingredients (INCI)

1 ingredient

Squalane

FREE FROM: Parabens, Sulfates, Phthalates, Fragrances, Essential Oils, Mineral Oil, Silicones, PEGs, Formaldehyde, Synthetic Dyes, Animal-Derived Ingredients, and 2,000+ potentially toxic or irritating ingredients banned by Biossance.

Where it fits in your routine

ROUTINE

Cleanser

Toner

Serum

Eye Cream

Moisturizer

Squalane Oil

Apply as the last step to lock in all previous products. For oily skin, apply to damp skin. Can also be mixed with moisturizer or used alone.

How to use

HOW TO USE

For Face

Warm 2-3 drops between palms. Pat gently onto face, neck, and décolleté after serums and moisturizer. For oily skin, apply to damp skin for lighter absorption.

For Body

Massage a few pumps onto skin immediately after showering while skin is still damp. Focus on dry areas like elbows, knees, and heels.

For Hair

Warm a small amount between hands and smooth through dry or wet hair to add shine and tame flyaways, split ends, and frizz. Can also be used as a scalp treatment.

For Lips

Apply a thin layer to lips to combat dryness and prep for color. Works great as an overnight lip treatment.

Who is it for?

WHO

Perfect for you if:

You want a single multi-purpose oil for face, body, and hair
You have dry, dehydrated, or aging skin
You need a fungal acne-safe moisturizing option
You're pregnant or breastfeeding and want safe hydration
You have sensitive or reactive skin
You want to boost absorption of other skincare products
You prefer clean, sustainable beauty products
You want a fragrance-free option

Consider alternatives if:

You're looking for additional active ingredients like vitamin C or retinol
You prefer a dropper over a pump dispenser
You're on a strict budget (more affordable dupes exist)
You want a scented oil experience
You need a mattifying finish (this has a dewy finish)

Skin type compatibility

SKIN TYPES

Oily Skin

Excellent

Lightweight and fast-absorbing. Apply to damp skin for non-greasy hydration. Helps balance oil production without clogging pores.

Dry Skin

Excellent

Provides deep, lasting hydration and locks in moisture. Can be layered generously or mixed with moisturizer for extra nourishment.

Combination Skin

Excellent

Balances well across different face zones. Use sparingly on T-zone and more generously on dry cheeks.

Sensitive Skin

Excellent

Hypoallergenic, fragrance-free, and non-irritating. Single ingredient formula minimizes risk of reactions.

Acne-Prone Skin

Excellent

Non-comedogenic (rating 0) and fungal acne safe. Won't clog pores or feed Malassezia yeast.

Mature Skin

Excellent

Replenishes squalene that skin loses with age. Promotes cell renewal and improves skin elasticity.

Results timeline

WEEK 5+

Immediately

Instant Hydration

Skin feels instantly hydrated, soft, and smooth. Absorbs quickly without leaving a greasy residue. Provides immediate comfort to dry, tight skin.

95% noticed instant hydration

Week 1

Improved Softness

Skin appears softer and smoother. Rough patches begin to improve. Overall texture feels more refined and supple.

95% noticed softer skin

Week 2

Enhanced Nourishment

Skin is noticeably more nourished and hydrated. Moisture barrier is strengthened. Dullness begins to diminish.

93% noticed improved hydration

Week 5+

Cell Renewal Boost

Increased cell renewal rate accelerates skin turnover by 5 days compared to untreated skin. Skin looks healthier and more radiant.

100% showed increased cell renewal

Ratings by platform

2K+ REVIEWS

Biossance.com

4.8

Rating

830+

Reviews

Main complaint: Price point is high compared to similar squalane oils

Sephora

4.3

Rating

500+

Reviews

Main complaint: Pump dispenses more product than needed

Amazon

4.6

Rating

1,200+

Reviews

Main complaint: Some concerns about product authenticity from third-party sellers

Cult Beauty

4.5

Rating

150+

Reviews

Main complaint: May feel slightly heavy for very oily skin types

Pros & cons

BALANCED

Praised

Ultra-lightweight and fast-absorbing
Versatile: works on face, body, hair, and lips
Single, pure ingredient with no additives
Safe for all skin types including sensitive
Fungal acne and pregnancy safe
Sustainable, shark-friendly sourcing
Large 100ml bottle lasts a long time
Convenient pump dispenser
No fragrance or irritating ingredients
Visible results backed by clinical studies

Criticized

Higher price point than drugstore alternatives
Pump can dispense too much product
No additional active ingredients
Dewy finish may not suit those wanting matte
Plastic packaging (though recyclable)
Some prefer dropper for precise application

Budget-friendly alternatives (dupes)

DUPES

100% Match

The Ordinary 100% Plant-Derived Squalane

$7.90

Budget Pick

Identical single-ingredient formula at a fraction of the price. Comes with dropper instead of pump. Source may vary (not specified as sugarcane). Slightly thicker texture.

100% Match

Good Molecules Squalane Oil

$8.00

Budget Pick

Same 100% squalane formula. Olive-derived (slightly thicker texture). Smaller 13ml bottle but excellent value. Glass dropper packaging.

100% Match

Timeless Skin Care Squalane Oil 100% Pure

$14.00

Similar Price

Olive-derived squalane with medium-weight texture. 2oz bottle with bamboo dropper. Over 5,000 reviews on Amazon. Works well as makeup primer too.

100% Match

Indeed Labs Squalane Facial Oil

$12.99

Budget Pick

Sugarcane-derived like Biossance. Ultra-light "dry oil" texture that sinks in quickly. Clinical-grade formula. May not be hydrating enough for very dry skin.

Comparison with competitors

SIDE-BY-SIDE

Biossance 100% Squalane Oil (Featured)

Key Ingredient 100% Sugarcane Squalane

Size 100ml / 3.3oz

Price per oz $9.70/oz

Packaging Pump Bottle

Texture Ultra-Lightweight

Fungal Acne Safe Yes

The Ordinary 100% Squalane

Key Ingredient 100% Plant-Derived Squalane

Size 30ml / 1oz

Price per oz $7.90/oz

Packaging Dropper Bottle

Texture Medium-Weight

Fungal Acne Safe Yes

Good Molecules Squalane Oil

Key Ingredient 100% Olive-Derived Squalane

Size 13ml / 0.44oz

Price per oz $18.18/oz

Packaging Glass Dropper

Texture Slightly Thicker

Fungal Acne Safe Yes

Timeless Squalane Oil 100% Pure

Key Ingredient 100% Olive-Derived Squalane

Size 60ml / 2oz

Price per oz $7.00/oz

Packaging Bamboo Dropper

Texture Medium-Weight

Fungal Acne Safe Yes

Storage & shelf life

12 MONTHS

Period After Opening (PAO)

12 months after opening. Squalane is highly stable and resistant to oxidation.

Storage

Store in a cool, dry place away from direct sunlight. No refrigeration required. Keep bottle closed when not in use.

Packaging

Recyclable pump bottle. Once empty, dispose of pump and rinse bottle for curbside recycling. Outer carton is FSC-certified sugarcane paper.

Travel Friendly

100ml size exceeds TSA carry-on limits. Travel size (30ml) available separately for air travel. Pump bottle is spill-resistant.

Frequently asked questions

FAQ

Is Biossance 100% Squalane Oil pregnancy and breastfeeding safe?

Yes, absolutely. This product contains only 100% pure squalane with no retinoids, salicylic acid, hydroquinone, chemical sunscreens, or any other ingredients that are contraindicated during pregnancy. Squalane is considered completely safe for use throughout pregnancy and breastfeeding. The only precaution: avoid applying to areas that may come in contact with baby's mouth while nursing.

Is Biossance 100% Squalane Oil fungal acne (malassezia) safe?

Yes, this is one of the safest oils for fungal acne-prone skin. Sugarcane-derived squalane is a hydrocarbon (made only of carbon and hydrogen), not a fatty acid or triglyceride. Malassezia yeast cannot metabolize squalane, making it completely safe. In fact, dermatologists often recommend squalane as one of the few oils that won't trigger fungal acne flares.

Can I use Biossance 100% Squalane Oil with retinol, vitamin C, AHA, or BHA?

Yes, squalane is compatible with all actives including retinol, vitamin C, AHAs, BHAs, niacinamide, and peptides. It has no pH concerns or interaction issues. In fact, applying squalane after these actives can help seal them in, reduce irritation, and enhance their absorption. It's an excellent "finishing" product for any routine.

What skin type is Biossance 100% Squalane Oil best for?

This squalane oil works excellently for all skin types: dry (deep hydration), oily (apply to damp skin for lightweight moisture), combination (adjust amount by zone), sensitive (hypoallergenic single ingredient), acne-prone (non-comedogenic), and mature (replaces naturally declining squalene). Its versatility is one of its greatest strengths.

How long until I see results from Biossance 100% Squalane Oil?

Instant results: 95% of users feel immediately hydrated skin. Week 1: Skin feels softer and smoother. Week 2: 93% notice improved nourishment and hydration. Week 5+: Clinical studies show 100% of users experienced increased cell renewal rate, with skin turnover accelerating by 5 days.

Where does Biossance 100% Squalane Oil go in my skincare routine?

Apply as your last step (after moisturizer) to seal in all previous products. The order is: Cleanser → Toner → Serum → Eye Cream → Moisturizer → Squalane Oil. You can also mix a few drops into your moisturizer, use it alone on damp skin, or apply it any time your skin needs extra hydration.

Is Biossance 100% Squalane Oil comedogenic / will it clog pores?

No, squalane has a comedogenic rating of 0-1, meaning it is non-comedogenic and will not clog pores. It's one of the few oils recommended for acne-prone skin. Biossance's formula is dermatologist tested, hypoallergenic, and specifically designed to be safe for all skin types including acne-prone.

How long does Biossance 100% Squalane Oil last after opening?

The product has a PAO (Period After Opening) of 12 months. Squalane is the hydrogenated, stable form of squalene, which means it's highly resistant to oxidation and has a long shelf life. Store in a cool, dry place away from direct sunlight for best results.

— Skincarisma verdict

4.6 / 5 ★★★★★

Verdict: Biossance 100% Squalane Oil is a premium, sustainably-sourced hydration powerhouse that delivers on its promises. Its single-ingredient purity makes it ideal for sensitive skin, fungal acne sufferers, and pregnant/breastfeeding individuals. While budget alternatives like The Ordinary offer similar formulas at lower prices, Biossance's ultra-lightweight sugarcane-derived texture, convenient pump packaging, and commitment to saving 2 million sharks annually justify the premium for those who value clean beauty and sustainability. A versatile must-have for any skincare routine.

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Product overview

Bioidentical Hydration

Texture & feel

Bioidentical Hydration

Boosts Active Absorption

Sustainable Sourcing

Microbiome Support

Safety & compatibility

Ingredient breakdown

Squalane 100%Proven

Where it fits in your routine

How to use

For Face

For Body

For Hair

For Lips

Who is it for?

Perfect for you if:

Consider alternatives if:

Skin type compatibility

Results timeline

Instant Hydration

Improved Softness

Enhanced Nourishment

Cell Renewal Boost

Ratings by platform

Pros & cons

Praised

Criticized

Budget-friendly alternatives (dupes)

Comparison with competitors

Biossance 100% Squalane Oil (Featured)

The Ordinary 100% Squalane

Good Molecules Squalane Oil

Timeless Squalane Oil 100% Pure

Storage & shelf life

Frequently asked questions

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